Tylan 200 ad us. vet.

Hauptinformation

  • Handelsname:
  • Tylan® 200 ad us. vet., Injektionslösung
  • Darreichungsform:
  • Injektionslösung
  • Verwenden für:
  • Tiere
  • Art der Medizin:
  • allopathic Droge

Dokumenten

  • Information für medizinisches Fachpersonal:
  • Das Informationsblatt für dieses Produkt ist derzeit nicht verfügbar, können Sie eine Anfrage an unseren Kundendienst zu senden und wir werden Sie benachrichtigen, sobald wir in der Lage, um es zu erhalten.


    Fordern Sie die Packungsbeilage für medizinisches Fachpersonal.

Lokalisierung

  • Erhältlich in:
  • Tylan® 200 ad us. vet., Injektionslösung
    Schweiz
  • Sprache:
  • Deutsch

Therapeutische Informationen

  • Therapiegruppe:
  • Makrolid-Antibiotikum für Rinder, Kälber und Schweine

Weitere Informationen

Status

  • Quelle:
  • Institut für Veterinärpharmakologie
  • Zulassungsnummer:
  • 33047
  • Letzte Änderung:
  • 02-09-2017

Packungsbeilage: zusammensetzung, kinische angaben, nebenwirkungen, wechselwirkungen, dosierung, schwangerschaft, stillzeit

Tylan

200 ad us. vet., Injektionslösung

Elanco Tiergesundheit AG

Makrolid-Antibiotikum für Rinder, Kälber und Schweine

ATCvet: QJ01FA90

Zusammensetzung

1 ml enthält: Tylosin 200 mg, Propylenglycol, Konservierungsmittel: Benzylalkohol 0,04 ml

in wässriger Lösung.

Fachinformationen Wirkstoffe (CliniPharm)

Tylosin

Eigenschaften / Wirkungen

Tylan

ist ein Fermentationsprodukt mit antibiotischem Charakter. Es wurde in den Lilly-

Forschungslaboratorien aus einer in Thailand entnommenen Bodenprobe isoliert, welche

einen Stamm von Streptomyces fradiae enthielt.

Tylan

gehört zu den Makrolid-Antibiotika. Es bindet sich an die ribosomale 50s-

Untereinheit von Prokaryonten und verhindert damit die Proteinsynthese. Tylan

wirkt im

allgemeinen bakteriostatisch, in hoher Konzentration auch bakterizid. Tylan

ist wirksam

gegen Mykoplasmen und grampositive Bakterien.

Pharmakokinetik

Nach parenteraler Verabreichung reichert sich Tylosin innerhalb von wenigen Stunden in

verschiedenen Geweben an wie Euter, Uterus, Lunge, Haut, Schleimhäute. Tylosin ist

basisch, deshalb erfolgt eine Konzentration besonders auch in Makrophagen und in

entzündeten Geweben. Die Serumwerte erreichen bei parenteraler oder oraler

Verabreichung nach 1 bis 5 Stunden ihr Maximum, anschliessend fallen sie rasch ab.

Hingegen können therapeutische Gewebespiegel während bis zu 24 Stunden gemessen

werden. Tylosin wird wenig metabolisiert, vier verschiedene Metaboliten sind bekannt.

Beim Schwein wird Tylosin hauptsächlich im Kot ausgeschieden.

Indikationen

Infektionen mit Mykoplasmen und grampositiven Erregern bei Rindern, Kälbern und

Schweinen.

Diese Injektionslösung ist intramuskulär oder bei Rindern auch langsam i.v. zu applizieren.

Rinder, Kälber, Schweine, Läufer, Ferkel:

0,5 ml Tylan

200 pro 10 kg Körpergewicht und Tag (= 10 mg Tylosin pro kg).

Mastitis bei laktierenden Kühen: Je eine Injektion mit der obenstehenden Dosierung an

3 aufeinanderfolgenden Tagen.

Um Unter- und Überdosierungen zu vermeiden, sollen Körpergewicht und Dosis vor

Behandlungsbeginn möglichst genau bestimmt werden.

Anwendungseinschränkungen

Kontraindikationen

Überempfindlichkeit gegenüber Bestandteilen des Präparates oder andere Makrolide.

Resistenz gegen Tylosin bzw. Kreuzresistenz gegen andere Makrolid-Antibiotika (MLS-

Resistenz).

Nicht bei Pferden anwenden.

Vorsichtsmassnahmen

Überdosierungen beim neugeborenen Ferkel können zu Schockreaktionen führen.

Bei wiederholten Injektionen ist die Injektionsstelle zu wechseln.

Die Anwendung des Tierarzneimittels sollte unter Berücksichtigung eines Antibiogramms

und entsprechend den offiziellen Regelungen zum Einsatz von Antibiotika erfolgen.

Unerwünschte Wirkungen

VetVigilance: Pharmacovigilance-Meldung erstatten

Nach intramuskulärer Injektion von Tylosin ist mit starker Reizung und lokaler

Gewebsdestruktion (demarkierten Nekrosen) zu rechnen, die in ihren Umbauvorgängen

bis zu 30 Tagen nachweisbar sind.

Allergische Reaktionen können auftreten.

Bei Schweinen können vereinzelt Oedeme der rektalen Schleimhaut mit leichtem Vorfall

des Enddarmes, Diarrhoe, Erythem und Pruritus auftreten, die jedoch nach Absetzen der

Behandlung komplikationslos abklingen.

Milch:

3 Tage

Essbares Gewebe:

Rinder, Kälber

7 Tage

Schweine

3 Tage

Injektionsstelle

21 Tage

Wechselwirkungen

Keine bekannt.

Sonstige Hinweise

Nicht mit anderen Injektionslösungen mischen.

Bei Raumtemperatur (15 - 25°C) und vor Licht geschützt aufbewahren.

Aufbrauchfrist nach 1. Entnahme: 28 Tage

Auf jeder Packung ist das Verfalldatum angegeben; das Präparat soll nicht über dieses

Datum hinaus verwendet werden.

Ausserhalb der Reichweite von Kindern aufbewahren!

Besondere Vorsichtsmassnahmen für den Anwender

-Bei versehentlicher Selbstinjektion ist unverzüglich ein Arzt zu Rate zu ziehen.

Im Fall einer Hautexposition waschen Sie das betroffene Hautareal sofort nach dem

Kontakt mit Wasser und Seife ab.

Im Fall einer Augenexposition spülen Sie die Augen sofort mit reichlich frischem Wasser

aus.

Tylosin kann Irritationen verursachen. Makrolide, wie auch Tylosin, können

Überempfindlichkeitsreaktionen (Allergie) als Folge von Injektion, Inhalation, Ingestion

oder Haut- bzw. Augenkontakt auslösen. Überempfindlichkeitsreaktionen auf Tylosin

können zu Kreuzreaktionen mit anderen Makroliden führen und umgekehrt. Gelegentlich

können allergische Reaktionen gegenüber diesen Substanzen schwerwiegend sein. Ein

Anschwellen des Gesichts, der Lippen und der Augenlieder oder Atemschwierigkeiten

gelten als schwerwiegendere Symptome und erfordern dringend ärztliche Hilfe.

Personen mit bekannter Überempfindlichkeit gegenüber einem der Inhaltsstoffe sollten

den Kontakt mit dem Tierarzneimittel vermeiden oder das Tierarzneimittel vorsichtig

anwenden.

Packungen

Flacon zu 100 ml

Abgabekategorie: A

Hersteller

Eli Lilly and Company Limited,

Speke Operations, Liverpool L24 9LN, United Kingdom

Swissmedic Nr. 33'047

Informationsstand: 09/2015

Dieser Text ist behördlich genehmigt.

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Versican Plus L4 ad us. vet.

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Institut für Veterinärpharmakologie und toxikologie

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● Änderung Text "Kurzbezeichnung", "Zusammensetzung", "Indikationen", "Dosierung / Anwendung", "Anwendungseinschränkungen", "Unerwünschte Wirkungen" und "Wechselwirkungen"

Institut für Veterinärpharmakologie und toxikologie

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The red palm weevil:  combating the loss of palm trees on the Mediterranean coast

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15-12-2018

Annual report of the Scientific Network on Microbiological Risk Assessment 2018

Annual report of the Scientific Network on Microbiological Risk Assessment 2018

Published on: Fri, 14 Dec 2018 Among the tasks of EFSA, according to its founding regulation (Regulation (EC) No 178/2002), there is the establishment of a system of Networks of organisations operating in the fields within EFSA's mission, the objective being to facilitate a scientific cooperation framework by the coordination of activities, the exchange of information, the development and implementation of joint projects, the exchange of expertise and best practices. Additionally, the EFSA Science Strat...

Europe - EFSA - European Food Safety Authority Publications

15-12-2018

Schauma-Dip ad us. vet., Zitzendesinfektionsmittel

Schauma-Dip ad us. vet., Zitzendesinfektionsmittel

● Neue Zulassungsinhaberin: Halag Chemie AG

Institut für Veterinärpharmakologie und toxikologie

14-12-2018

Response to comments on the Scientific Opinion on the scientific substantiation of a health claim related to Symbiosal® and lowering of blood pressure and reduced risk of hypertension pursuant to Article 14 of Regulation (EC) No 1924/2006

Response to comments on the Scientific Opinion on the scientific substantiation of a health claim related to Symbiosal® and lowering of blood pressure and reduced risk of hypertension pursuant to Article 14 of Regulation (EC) No 1924/2006

Published on: Thu, 13 Dec 2018 Following a request from the European Commission, EFSA was asked to review the comments received on the Scientific Opinion of the EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA) on the scientific substantiation of a health claim related to Symbiosal® and lowering of blood pressure and reduced risk of hypertension pursuant to Article 14 of Regulation (EC) No 1924/2006. Comments originating from the applicant (Han‐Biotech GmbH) were submitted to EFSA via the E...

Europe - EFSA - European Food Safety Authority Publications

14-12-2018

Bovilis BTV8 ad us. vet.

Bovilis BTV8 ad us. vet.

● Die Zulassung ist am 14.12.2018 erloschen.

Institut für Veterinärpharmakologie und toxikologie

13-12-2018

The European Union summary report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in 2017

The European Union summary report on trends and sources of zoonoses, zoonotic agents and food-borne outbreaks in 2017

Published on: Wed, 12 Dec 2018 This report of the European Food Safety Authority and the European Centre for Disease Prevention and Control presents the results of zoonoses monitoring activities carried out in 2017 in 37 European countries (28 Member States (MS) and nine non-MS). Campylobacteriosis was the commonest reported zoonosis and its EU trend for confirmed human cases increasing since 2008 stabilised during 2013–2017. The decreasing EU trend for confirmed human salmonellosis cases since 2008 end...

Europe - EFSA - European Food Safety Authority Publications

12-12-2018

Activyl TickPlus spot-on Hund XS ad us. vet., insektizide Loesung zum Auftragen auf die Haut

Activyl TickPlus spot-on Hund XS ad us. vet., insektizide Loesung zum Auftragen auf die Haut

● Umwandlung in Exportzulassung (Exportspezialität): nur für den Vertrieb im Ausland

Institut für Veterinärpharmakologie und toxikologie

12-12-2018

Activyl TickPlus spot-on Hund S ad us. vet., insektizide Loesung zum Auftragen auf die Haut

Activyl TickPlus spot-on Hund S ad us. vet., insektizide Loesung zum Auftragen auf die Haut

● Umwandlung in Exportzulassung (Exportspezialität): nur für den Vertrieb im Ausland

Institut für Veterinärpharmakologie und toxikologie

12-12-2018

Activyl TickPlus spot-on Hund M ad us. vet., insektizide Loesung zum Auftragen auf die Haut

Activyl TickPlus spot-on Hund M ad us. vet., insektizide Loesung zum Auftragen auf die Haut

● Umwandlung in Exportzulassung (Exportspezialität): nur für den Vertrieb im Ausland

Institut für Veterinärpharmakologie und toxikologie

12-12-2018

Activyl TickPlus spot-on Hund L ad us. vet., insektiztide Loesung zum Auftragen auf die Haut

Activyl TickPlus spot-on Hund L ad us. vet., insektiztide Loesung zum Auftragen auf die Haut

● Umwandlung in Exportzulassung (Exportspezialität): nur für den Vertrieb im Ausland

Institut für Veterinärpharmakologie und toxikologie

12-12-2018

Activyl TickPlus spot-on Hund XL ad us. vet., insektizide Loesung zum Auftragen auf die Haut

Activyl TickPlus spot-on Hund XL ad us. vet., insektizide Loesung zum Auftragen auf die Haut

● Umwandlung in Exportzulassung (Exportspezialität): nur für den Vertrieb im Ausland

Institut für Veterinärpharmakologie und toxikologie

12-12-2018

Carofertin ad us. vet., Injektionsemulsion

Carofertin ad us. vet., Injektionsemulsion

● Die Neuzulassung erfolgte am 12.12.2018.

Institut für Veterinärpharmakologie und toxikologie

11-12-2018

Simparica 5 mg ad us. vet., Kautabletten fuer Hunde

Simparica 5 mg ad us. vet., Kautabletten fuer Hunde

● Indikationserweiterung (Demodex canis, Otodectes cynotis) ● Änderung Text "Eigenschaften / Wirkungen", "Indikationen", "Dosierung / Anwendung" und "Unerwünschte Wirkungen"

Institut für Veterinärpharmakologie und toxikologie

11-12-2018

Simparica 10 mg ad us. vet., Kautabletten fuer Hunde

Simparica 10 mg ad us. vet., Kautabletten fuer Hunde

● Indikationserweiterung (Demodex canis, Otodectes cynotis) ● Änderung Text "Eigenschaften / Wirkungen", "Indikationen", "Dosierung / Anwendung" und "Unerwünschte Wirkungen"

Institut für Veterinärpharmakologie und toxikologie

11-12-2018

Simparica 20 mg ad us. vet., Kautabletten fuer Hunde

Simparica 20 mg ad us. vet., Kautabletten fuer Hunde

● Indikationserweiterung (Demodex canis, Otodectes cynotis) ● Änderung Text "Eigenschaften / Wirkungen", "Indikationen", "Dosierung / Anwendung" und "Unerwünschte Wirkungen"

Institut für Veterinärpharmakologie und toxikologie

11-12-2018

Simparica 40 mg ad us. vet., Kautabletten fuer Hunde

Simparica 40 mg ad us. vet., Kautabletten fuer Hunde

● Indikationserweiterung (Demodex canis, Otodectes cynotis) ● Änderung Text "Eigenschaften / Wirkungen", "Indikationen", "Dosierung / Anwendung" und "Unerwünschte Wirkungen"

Institut für Veterinärpharmakologie und toxikologie

10-1-2019

Mifegyne 200 mg Tabletten

Rote - Liste

20-12-2018

.@US_FDA provides an update on new steps to revise #Essure's post-market study to collect long-term safety information following discontinuation of its U.S. sales. Read FDA Commissioner @SGottliebFDA's statement on the new steps here:  https://go.usa.gov/

.@US_FDA provides an update on new steps to revise #Essure's post-market study to collect long-term safety information following discontinuation of its U.S. sales. Read FDA Commissioner @SGottliebFDA's statement on the new steps here: https://go.usa.gov/

. @US_FDA provides an update on new steps to revise #Essure's post-market study to collect long-term safety information following discontinuation of its U.S. sales. Read FDA Commissioner @SGottliebFDA's statement on the new steps here: https://go.usa.gov/xEaNB  #MedicalDevice

FDA - U.S. Food and Drug Administration

19-12-2018

Join us on January 17, 2019 from 1-2:30 PM EST for a webinar to help clarify the Breakthrough Devices Program final guidance for manufacturers. Find out more about the webinar:  https://go.usa.gov/xExHX  #MedicalDevice #FDApic.twitter.com/sHElqFFODy

Join us on January 17, 2019 from 1-2:30 PM EST for a webinar to help clarify the Breakthrough Devices Program final guidance for manufacturers. Find out more about the webinar: https://go.usa.gov/xExHX  #MedicalDevice #FDApic.twitter.com/sHElqFFODy

Join us on January 17, 2019 from 1-2:30 PM EST for a webinar to help clarify the Breakthrough Devices Program final guidance for manufacturers. Find out more about the webinar: https://go.usa.gov/xExHX  #MedicalDevice #FDA pic.twitter.com/sHElqFFODy

FDA - U.S. Food and Drug Administration

19-12-2018

On Dec. 18th, the @US_FDA issued the final guidance on the Breakthrough Devices Program. The guidance outlines program policies, features, and the process for manufacturers to follow when choosing to pursue the #breakthrough designation. Read more:  https

On Dec. 18th, the @US_FDA issued the final guidance on the Breakthrough Devices Program. The guidance outlines program policies, features, and the process for manufacturers to follow when choosing to pursue the #breakthrough designation. Read more: https

On Dec. 18th, the @US_FDA issued the final guidance on the Breakthrough Devices Program. The guidance outlines program policies, features, and the process for manufacturers to follow when choosing to pursue the #breakthrough designation. Read more: https://go.usa.gov/xExHq  pic.twitter.com/fAAZAQx1H5

FDA - U.S. Food and Drug Administration

19-12-2018

On 12/12/18 GE Healthcare Recalled CareScape R860 Inspiratory Safety Guard Due to Risk of Disconnection from Breathing Circuit. @US_FDA has identified this as a Class I Recall, the most serious type recall. Read more about the recall:  https://go.usa.gov/

On 12/12/18 GE Healthcare Recalled CareScape R860 Inspiratory Safety Guard Due to Risk of Disconnection from Breathing Circuit. @US_FDA has identified this as a Class I Recall, the most serious type recall. Read more about the recall: https://go.usa.gov/

On 12/12/18 GE Healthcare Recalled CareScape R860 Inspiratory Safety Guard Due to Risk of Disconnection from Breathing Circuit. @US_FDA has identified this as a Class I Recall, the most serious type recall. Read more about the recall: https://go.usa.gov/xE383  #MedicalDevice #FDA pic.twitter.com/S2EbMdmwpe

FDA - U.S. Food and Drug Administration

19-12-2018

ISOZID® comp. 100/200/300 mg N

Rote - Liste

19-12-2018

Ciprobay® 200 mg

Rote - Liste

18-12-2018

#DYK December is #SafeToysAndGiftsMonth. Check out @US_FDA's Consumer Update on how to keep kids safe with toys containing lasers:  https://go.usa.gov/xEx2r  #FDApic.twitter.com/57pZAmSb9r

#DYK December is #SafeToysAndGiftsMonth. Check out @US_FDA's Consumer Update on how to keep kids safe with toys containing lasers: https://go.usa.gov/xEx2r  #FDApic.twitter.com/57pZAmSb9r

#DYK December is #SafeToysAndGiftsMonth. Check out @US_FDA's Consumer Update on how to keep kids safe with toys containing lasers: https://go.usa.gov/xEx2r  #FDA pic.twitter.com/57pZAmSb9r

FDA - U.S. Food and Drug Administration

18-12-2018


Orphan designation: Mercaptopurine (oral suspension), Treatment of acute lymphoblastic leukaemia, 30/04/2009, Positive

Orphan designation: Mercaptopurine (oral suspension), Treatment of acute lymphoblastic leukaemia, 30/04/2009, Positive

Orphan designation: Mercaptopurine (oral suspension), Treatment of acute lymphoblastic leukaemia, 30/04/2009, Positive

Europe - EMA - European Medicines Agency

14-12-2018

GE Healthcare Recalls CareScape R860 Inspiratory Safety Guard Due to Risk of Disconnection from Breathing Circuit. @US_FDA @US has identified this as a Class I Recall, the most serious type recall. Read more about the recall here:  https://go.usa.gov/xE38

GE Healthcare Recalls CareScape R860 Inspiratory Safety Guard Due to Risk of Disconnection from Breathing Circuit. @US_FDA @US has identified this as a Class I Recall, the most serious type recall. Read more about the recall here: https://go.usa.gov/xE38

GE Healthcare Recalls CareScape R860 Inspiratory Safety Guard Due to Risk of Disconnection from Breathing Circuit. @US_FDA @US has identified this as a Class I Recall, the most serious type recall. Read more about the recall here: https://go.usa.gov/xE383  #MedicalDevice #FDA pic.twitter.com/X4IprwU8R2

FDA - U.S. Food and Drug Administration

14-12-2018

#ICYMI: @US_FDA cleared a mobile medical app to help those with #opioid use disorder stay in recovery programs. Read more about the clearance here:  https://go.usa.gov/xE3ke  #FDA #MedicalDevice

#ICYMI: @US_FDA cleared a mobile medical app to help those with #opioid use disorder stay in recovery programs. Read more about the clearance here: https://go.usa.gov/xE3ke  #FDA #MedicalDevice

#ICYMI: @US_FDA cleared a mobile medical app to help those with #opioid use disorder stay in recovery programs. Read more about the clearance here: https://go.usa.gov/xE3ke  #FDA #MedicalDevice

FDA - U.S. Food and Drug Administration