Panacur Boli 250 ad us. vet.

Hauptinformation

  • Handelsname:
  • Panacur® Boli 250 ad us. vet.
  • Darreichungsform:
  • Panacur® Boli 250 ad us. vet.
  • Verwenden für:
  • Tiere
  • Art der Medizin:
  • allopathic Droge

Dokumenten

  • Information für medizinisches Fachpersonal:
  • Das Informationsblatt für dieses Produkt ist derzeit nicht verfügbar, können Sie eine Anfrage an unseren Kundendienst zu senden und wir werden Sie benachrichtigen, sobald wir in der Lage, um es zu erhalten.


    Fordern Sie die Packungsbeilage für medizinisches Fachpersonal.

Lokalisierung

  • Erhältlich in:
  • Panacur® Boli 250 ad us. vet.
    Schweiz
  • Sprache:
  • Deutsch

Therapeutische Informationen

  • Therapiegruppe:
  • Breitspektrum-Anthelmin­thi­kum gegen unreife und reife Stadien von Magen-Darm-Nematoden und Lungenwürmern sowie gegen Bandwürme

Weitere Informationen

Status

  • Quelle:
  • Institut für Veterinärpharmakologie
  • Zulassungsnummer:
  • 41039
  • Letzte Änderung:
  • 02-09-2017

Packungsbeilage

Panacur

Boli 250 ad us. vet.

MSD Animal Health GmbH

Breitspektrum-Anthelminthikum gegen unreife und reife Stadien von Magen-Darm-

Nematoden und Lungenwürmern sowie gegen Bandwürmer bei Schafen

ATCvet: QP52AC13

Zusammensetzung

Wirkstoff: Fenbendazolum

250 mg

-Hilfsstoffe: Excip. pro bolo

-galenische Form: Boli

Fachinformationen Wirkstoffe (CliniPharm)

Fenbendazol

Eigenschaften / Wirkungen

Der grundlegende Mechanismus der anthelminthischen Wirkung von Fenbendazol ist eine

Hemmung der Polymerisation von Tubulin zu Mikrotubuli. Dadurch werden wichtige

strukturelle Eigenschaften der Helminthenzelle beeinträchtigt, wie die Ausbildung des

Zytoskeletts, die Spindelbildung bei der Mitose sowie Aufnahme und intrazellulärer

Transport von Nährstoffen und Stoffwechselsubstraten. Als Folge kommt es zu einer

Erschöpfung der Energiereserven mit nachfolgendem Absterben des Parasiten und seiner

Expulsion nach 2 - 3 Tagen.

Fenbendazol besitzt eine ovizide Wirkung, die nach ca. 8 Stunden infolge einer Störung

der Spindelbildung und des Metabolismus während der Embryogenese eintritt.

Fenbendazol ist hochwirksam gegen adulte und immature Magen-Darm-Nematoden und

Lungenwürmer, sowie gegen inhibierte und histotrope Larvenstadien. Darüber hinaus zeigt

Fenbendazol eine gute Wirksamkeit gegen verschiedene Bandwurmarten.

Die Verabreichung von Panacur

Boli an Mutterschafe kann in jedem Stadium der

Trächtigkeit oder Laktation erfolgen.

Pharmakokinetik

Fenbendazol wird nach oraler Applikation zum Teil resorbiert und dann zu einem

erheblichen Teil in der Leber metabolisiert. Die Resorption erfolgt bei Tieren mit

einhöhligem Magen schneller als bei Wiederkäuern. Als Hauptmetaboliten werden ein

Sulfoxid und ein Sulfon-Metabolit gebildet.

Die Halbwertzeit von Fenbendazol im Serum beträgt nach oraler Applikation der

empfohlenen Dosis speziesabhängig zwischen 10 und 33 Stunden. Fenbendazol und

seine Metaboliten verteilen sich im Gesamtorganismus, wobei hohe Konzentrationen in

der Leber erreicht werden. Die Ausscheidung von unverändertem und metabolisiertem

Fenbendazol erfolgt überwiegend (> 90%) über den Kot, zu geringem Teil auch über den

Urin und die Milch.

Indikationen

Befall von Schafen mit Magen-Darm-Nematoden, Lungenwürmern und Bandwürmern wie

Haemonchus spp., Ostertagia spp., Trichostrongylus spp., Cooperia spp., Nematodirus

spp., Oesophagostomum spp., Chabertia spp., Bunostomum spp., Gaigeria pachyscelis,

Trichuris spp., Strongyloides spp., Dictyocaulus filaria, Moniezia spp.

Körper-

gewicht

(KGW)

Befall mit

Magen−Darm− und

Lungenwürmern

Befall mit

Bandwürmern

Richtdosis:

5 mg Fenbendazol

/kg KGW

Richtdosis:

10 mg Fenbendazol

/kg KGW

25 kg

½ Bolus

1 Bolus

50 kg

1 Bolus

2 Boli

75 kg

1 ½ Boli

3 Boli

Es empfiehlt sich, Panacur

Boli 250 mit einem Pilleneingeber zu verabreichen. Es ist

darauf zu achten, dass die Boli abgeschluckt werden. Diätmassnahmen vor oder nach der

Behandlung sind nicht erforderlich. Nach Neuinfektionen ist die Behandlung zu

wiederholen.

Anwendungseinschränkungen

Kontraindikationen

Keine.

Vorsichtsmassnahmen:

Keine.

Unerwünschte Wirkungen

VetVigilance: Pharmacovigilance-Meldung erstatten

Keine bekannt.

Leber:

21 Tage

Übrige essbare Gewebe:14 Tage

Milch:

6 Tage

Wechselwirkungen

Eine gleichzeitige Anwendung mit Präparaten zur Leberegelbekämpfung ist wegen der

Möglichkeit von Unverträglichkeitserscheinungen zu vermeiden.

Sonstige Hinweise

Lagerung bei Raumtemperatur (15 - 25°C).

Medikament, für Kinder unzugänglich aufbewahren.

Packungen

Schachtel mit 50 Boli

Abgabekategorie: B

Swissmedic Nr. 41'039

Informationsstand: 06/2005

Dieser Text ist behördlich genehmigt.

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