Marfloquin S 10% ad us. vet.[E]

Hauptinformation

  • Handelsname:
  • Marfloquin® S 10% ad us. vet.[E], Injektionslösung
  • Darreichungsform:
  • Injektionslösung
  • Verwenden für:
  • Tiere
  • Art der Medizin:
  • allopathic Droge

Dokumenten

  • Information für medizinisches Fachpersonal:
  • Das Informationsblatt für dieses Produkt ist derzeit nicht verfügbar, können Sie eine Anfrage an unseren Kundendienst zu senden und wir werden Sie benachrichtigen, sobald wir in der Lage, um es zu erhalten.


    Fordern Sie die Packungsbeilage für medizinisches Fachpersonal.

Lokalisierung

  • Erhältlich in:
  • Marfloquin® S 10% ad us. vet.[E], Injektionslösung
    Schweiz
  • Sprache:
  • Deutsch

Therapeutische Informationen

  • Therapiegruppe:
  • Antibiotikum (Gyrasehemmer) für Rinder und Kälber

Weitere Informationen

Status

  • Quelle:
  • Institut für Veterinärpharmakologie
  • Zulassungsnummer:
  • 62508
  • Letzte Änderung:
  • 02-09-2017

Packungsbeilage

Marfloquin

S 10% ad us. vet.

, Injektionslösung

Virbac (Switzerland) AG

HINWEIS: Exportspezialität (Nur für den Vertrieb im Ausland zugelassen)!

Antibiotikum (Gyrasehemmer) für Rinder und Kälber

ATCvet: QJ01MA93

Zusammensetzung

1 ml enthält:

Wirkstoff: Marbofloxacinum 100 mg

Hilfsstoffe: Gluconolactonum, Natrii edetas

Conserv.: m-cresolum 2 mg, Antiox.: Thioglycerolum 1 mg

Aqua ad injectabilia q.s. ad solutionem

Fachinformationen Wirkstoffe (CliniPharm)

Marbofloxacin

Eigenschaften / Wirkungen

Marbofloxacin ist ein synthetisches, bakterizides Antiinfektivum, das zur Familie der

Fluorochinolone gehört. Es wirkt über die Hemmung der DNA-Gyrase. Es besitzt in vitro

ein breites Wirkungsspektrum, das Gram-positive Bakterien (insbesondere

Staphylokokken), Gram-negative Keime (Escherichia coli, Pasteurella sp) und auch

Mykoplasmen einschliesst.

Pharmakokinetik

Nach einmaliger intramuskulärer Verabreichung beim Rind in der empfohlenen Dosierung

von 8 mg/kg, wird Marbofloxacin sehr rasch absorbiert (T

max obs

= 0.78 h ± 0.21 h).

Maximale Absorption wird erreicht mit C

max obs

= 7.349 ± 1.111 µg/ml und einer AUC

38.42 ± 5.186 µg.h/ml. Marbofloxacin wird langsam eliminiert (T½ß = 15.60 ± 3.24 h),

hauptsächlich in aktiver Form über Urin und Fäzes.

Indikationen

Zur Behandlung von Atemwegsinfektionen, welche durch Marbofloxacin-empfindliche

Stämme von Pasteurella multocida, Mannheimia (Pasteurella) haemolytica oder

Histophilus somni hervorgerufen werden.

8 mg Marbofloxacin pro kg KGW, entsprechend 4 ml MARFLOQUIN S 10% pro 50 kg

KGW, als Einmalinjektion intramuskulär. Pro Injektionsstelle darf maximal 20 ml injiziert

werden. Falls grössere Volumina appliziert werden, muss die Dosis auf mehrere

Injektionsstellen verteilt werden.

Anwendungseinschränkungen

Die Sicherheit des 8 mg/kg dosierten Medikamentes wurde für trächtige Kühe oder

saugende Kälber an damit behandelten Kühen nicht überprüft.

Kontraindikationen

Vorliegende Resistenz gegenüber Chinolonen, da gegenüber diesen eine nahezu

vollständige, gegenüber anderen Fluorchinolonen eine komplette Kreuzresistenz besteht.

Vorsichtsmassnahmen

MARFLOQUIN S 10% ad us. vet. soll nur nach bakteriologischer Sicherung der Diagnose

und Sensitivitätsprüfung der beteiligten Erreger sowie bei Vorliegen von Resistenzen

gegenüber anderen Antibiotika angewandt werden. Der Einsatz von MARFLOQUIN S 10%

ad us. vet., wie der aller Fluorochinolone, sollte aus Gründen einer möglichen

Resistenzentwicklung nicht bei geringfügigen Infektionen erfolgen. Fluorochinolone

können den Gelenkknorpel schädigen.

Unerwünschte Wirkungen

VetVigilance: Pharmacovigilance-Meldung erstatten

Die i.m. Applikation kann zu Entzündungen an der Injektionsstelle führen, die beim Kalb

12 Tage andauern.

Essbares Gewebe

Rind, Kalb: 3 Tage

Milch 2.5 Tage (5 Gemelke)

Wechselwirkungen

Die gleichzeitige Anwendung von MARFLOQUIN S 10% ad us. vet. mit Makroliden oder

Tetrazyklin ist zu unterlassen.

Sonstige Hinweise

Arzneimittel für Kinder unerreichbar aufbewahren.

Aufbrauchsfrist nach 1. Entnahme: 28 Tage.

Das Arzneimittel darf nur bis zu dem auf dem Behälter mit 'EXP' bezeichneten Datum

verwendet werden.

Bei Raumtemperatur (15 - 25°C) in der Originalpackung vor Licht geschützt lagern.

Packungen

Nur für den Vertrieb im Ausland bestimmt.

Exportspezialität: Vertrieb in der Schweiz nicht zugelassen!

Abgabekategorie: A

Swissmedic Nr. 62'508

Informationsstand: 08/2012

Dieser Text ist behördlich genehmigt.

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