Equest orales Gel ad us. vet.

Hauptinformation

  • Handelsname:
  • Equest® orales Gel ad us. vet.
  • Darreichungsform:
  • Equest® orales Gel ad us. vet.
  • Verwenden für:
  • Tiere
  • Art der Medizin:
  • allopathic Droge

Dokumenten

  • Information für medizinisches Fachpersonal:
  • Das Informationsblatt für dieses Produkt ist derzeit nicht verfügbar, können Sie eine Anfrage an unseren Kundendienst zu senden und wir werden Sie benachrichtigen, sobald wir in der Lage, um es zu erhalten.


    Fordern Sie die Packungsbeilage für medizinisches Fachpersonal.

Lokalisierung

  • Erhältlich in:
  • Equest® orales Gel ad us. vet.
    Schweiz
  • Sprache:
  • Deutsch

Therapeutische Informationen

  • Therapiegruppe:
  • Breitspektrum-Antiparasitikum für Pferde.

Weitere Informationen

Status

  • Quelle:
  • Institut für Veterinärpharmakologie
  • Zulassungsnummer:
  • 55162
  • Letzte Änderung:
  • 02-09-2017

Packungsbeilage

Equest

orales Gel ad us. vet.

Zoetis Schweiz GmbH

Breitspektrum-Antiparasitikum für Pferde.

ATCvet: QP54AB02

Zusammensetzung

1 g orales Gel enthält:

Moxidectin 18,92 mg, Conserv.: Benzylalkohol, Excip. ad gelatum.

Fachinformationen Wirkstoffe (CliniPharm)

Moxidectin

Eigenschaften / Wirkungen

Moxidectin ist ein Breitspektrum-Antiparasitikum mit Wirkung gegen eine Vielzahl von

Endo- und Ektoparasiten. Es ist ein makrozyklisches Lakton aus der Milbemycin-Familie.

Sein Wirkungsmechanismus besteht im Wesentlichen in der Beeinflussung der

neuromuskulären Übertragung der GABA (Gamma-Aminobuttersäure)-gesteuerten oder

der Glutamat-gesteuerten Chloridkanäle. Moxidectin stimuliert die Freisetzung von GABA

und verstärkt seine Bindung an die postsynaptischen Rezeptoren und bindet an die

Glutamat gesteuerten Chloridkanäle. Als Nettoeffekt resultiert die Öffnung der

Chloridkanäle an der postsynaptischen Membran, wodurch der Zustrom von Chloridionen

erhöht und ein irreversibler Ruhezustand induziert wird. Das führt zur schlaffen Lähmung

und schliesslich zum Tod der dem Arzneimittel ausgesetzten Parasiten.

Pharmakokinetik

Nach oraler Verabreichung wird Moxidectin resorbiert. Maximale Blutkonzentrationen

werden 8 Stunden nach Applikation erreicht. Die Bioverfügbarkeit ist 40%, die

Plasmahalbwertszeit 28 Tage. Der Wirkstoff wird über alle Körpergewebe verteilt. Wegen

seiner Lipophilie sind die Konzentrationen im Fett viel höher als in den übrigen Geweben.

Moxidectin wird langsam mit dem Kot ausgeschieden, zu 60% unverändert, der Rest in

Form verschiedener durch Hydroxylierung entstandener Metaboliten.

Indikationen

Equest

Orales Gel ist indiziert zur Behandlung von Infestationen durch folgende

Moxidectin-empfindliche Parasiten:

Grosse Strongyliden: Strongylus vulgaris (adulte und arterielle Stadien), Strongylus

edentatus (adulte und viszerale Stadien).

Kleine Strongyliden (adulte Stadien und enzystierte Larven):

Cyathostomum spp., Cylicocyclus spp., Cylicostephanus spp., Cylicodontophorus spp.,

Gyalocephalus spp., Triodontophorus brevicauda (adulte Stadien), Triodontophorus

servatus (adulte Stadien), Triodontophorus tenuicollis (adulte Stadien).

Das Tierarzneimittel ist wirksam gegen sich entwickelnde intramukosale L4 Stadien von

kleinen Strongyliden. 8 Wochen nach der Behandlung sind frühe, hypobiotische EL3-

Stadien der kleinen Strongyliden abgetötet.

Die Ausscheidung von Eiern kleiner Strongyliden wird während 90 Tagen unterdrückt.

Das Produkt ist gegen Benzimidazol resistente Stämme von kleinen Strongyliden

(Cyathostominae spp.) wirksam.

Spulwürmer: Parascaris equorum (adulte Stadien und Larven).

Andere Wurmarten: Oxyuris equi (adulte Stadien und Larven), Strongyloides westeri

(adulte Stadien), Trichostrongylus axei.

Insektenlarven: Habronema muscae (adulte Stadien), Gasterophilus intestinalis (L2, L3),

Gasterophilus nasalis (L2, L3).

Dosierung / Anwendung

Eine einzelne orale Dosis von 0,4 mg Moxidectin/kg KGW unter Verwendung des

kalibrierten Injektors (eine Unterteilung pro 25 kg Lebendgewicht) applizieren.

Es wird empfohlen, das Gewicht des Tieres mit einer Waage oder einem Gewichtsband zu

bestimmen, um eine genaue Dosierung zu gewährleisten.

Alle Tiere einer Gruppe müssen behandelt werden.

Ein einzelner Injektor ist ausreichend für ein 700 kg schweres Pferd.

Anwendung während der Trächtigkeit und Laktation

Das Tierarzneimittel hat sich als sicher in der Anwendung bei trächtigen und laktierenden

Stuten erwiesen.

Festlegung der Dosis

Da die Dosis vom Gewicht des Tieres abhängt, sollte ein Skalen- oder

Gewichtsmassband verwendet werden, um das Gewicht jeden Tieres festzustzellen,

bevor es mit Equest Gel behandelt wird. Nach Feststellung des Gewichtes, legen Sie die

Dosis für jedes Pferd oder Pony wie folgt fest:

Halten Sie die Spritze mit dem Kappenende nach links gerichtet und so, dass Sie die

Gewichtsmarkierungen und die kleinen schwarzen Markierungen, wie unten abgebildet,

sehen können. Jede kleine schwarze Markierung bezieht sich auf 25 kg Körpergewicht.

Drehen Sie den grünen Anzeigering, bis die linke Seite des Ringes das Gewicht des

Tieres markiert hat. In der Abbildung unten fixiert der Anzeigering die Dosis für ein

400 kg schweres Pferd.

Verabreichung der Dosis

Stellen Sie sicher, dass das Maul des Tieres leer ist. Mit Ihrem Daumen am Stempel

führen Sie die Spritzenkanüle in das Maul des Pferdes in die Lücke zwischen Vorder-

und Backenzähne (zahnfreie Lade). Stellen Sie sicher, dass die Spitze des Injektors über

dem hinteren Teil der Zunge liegt.

Verabreichen Sie eine Dosis Gel auf die hintere Zunge, indem Sie den Stempel sanft bis

zum Anschlag drücken.

Nach Verabreichung der Dosis heben Sie den Kopf des Pferdes an, um das

Abschlucken des Gels zu gewährleisten.

Anwendungseinschränkungen

Kontraindikationen

Nicht bei Fohlen, die jünger als 4 Monate sind, anwenden.

Nicht bei Stuten anwenden, deren Milch für den menschlichen Verzehr vorgesehen ist.

Vorsichtsmassnahmen

Um Überdosierungen zu vermeiden, sollte besonders bei leichtgewichtigen Fohlen oder

Ponyfohlen auf eine genaue Dosierung geachtet werden.

Nicht mehr als ein Tier mit derselben Applikationsspritze behandeln, es sei denn die

Pferde werden auf der Weide oder im Stall gemeinsam gehalten.

Bei Hunden und Katzen können auf Grund der Moxidectinkonzentration in Equest orales

Gel ad us. vet. Nebenwirkungen auftreten, wenn die Tiere ausgelaufenes Gel aufnehmen

oder Zugang zu benutzten Applikationsspritzen haben.

Unerwünschte Wirkungen

VetVigilance: Pharmacovigilance-Meldung erstatten

Unerwünschte Reaktionen können bei Fohlen nach Verabreichung der zweifachen Menge

der empfohlenen Dosis und bei erwachsenen Pferden nach Verabreichung der dreifachen

Menge der empfohlenen Dosis vorübergehend auftreten.

Die Symptome sind Abgeschlagenheit, Ataxie und Schlaffheit der Unterlippe 8 bis

24 Stunden nach der Behandlung. Im Allgemeinen ist eine Therapie nicht notwendig und

die Symptome klingen innerhalb von 24 bis 72 Stunden ab. Es gibt kein spezifisches

Gegenmittel. Bei Fohlen kann eine Überdosierung eine Fütterung mittels

Nasenschlundsonde erforderlich machen.

Bei sehr starkem Wurmbefall kann die Abtötung der Parasiten vorübergehend zu einer

leichten Kolik und zu weichem Kot bei dem behandelten Pferd führen.

Essbare Gewebe: 28 Tage

Wechselwirkungen

Keine bekannt.

Sonstige Hinweise

Arzneimittel für Kinder unzugänglich aufbewahren!

Arzneimittel unter 25°C lagern.

Das Arzneimittel nach Ablauf des auf Behältnis und äusserer Umhüllung angegebenen

Verfalldatums nicht mehr anwenden.

Arzneimittel innerhalb von 6 Monaten nach der Öffnung aufbrauchen.

Direkten Kontakt mit Haut und Augen vermeiden.

Während der Anwendung nicht essen, trinken oder rauchen.

Das Produkt darf nicht in Gewässer gelangen, da es für Fische und im Wasser lebende

Organismen toxisch sein kann.

Packungen

Schachtel mit Injektor à 14.8 g orales Gel.

Abgabekategorie: A

Swissmedic Nr. 55'162

Informationsstand: 07/2013

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National dietary survey in 2012‐2016 on the general population aged 1‐79 years in the Netherlands

National dietary survey in 2012‐2016 on the general population aged 1‐79 years in the Netherlands

Published on: Tue, 18 Sep 2018 00:00:00 +0200 During the years 2012‐2016, the Dutch National Food Consumption survey was conducted in the Netherlands. For the survey, a random sample was drawn from consumer panels stratified by age and gender and maintained representative to the population with regard to region, address density and educational level. Complete results were obtained for 4,313 persons (response rate 65%); including toddlers, children, adolescents, adults and elderly. Pregnant or lactating ...

Europe - EFSA - European Food Safety Authority Publications

18-9-2018

Lidl Voluntarily Recalls Bellona Brand Hazelnut Wafers Due to Improperly Declared Wheat Allergen

Lidl Voluntarily Recalls Bellona Brand Hazelnut Wafers Due to Improperly Declared Wheat Allergen

Lidl US has voluntarily recalled all Bellona brand “Milk Chocolate Flavored Coated Wafer with Hazelnut Crème Filling and White Chocolate Flavor” confections as a precautionary measure because the allergen statement does not include wheat.

FDA - U.S. Food and Drug Administration

14-9-2018

Minister van Sport Bruno Bruins aanwezig bij MXGP Assen

Minister van Sport Bruno Bruins aanwezig bij MXGP Assen

Dit weekend staat de Motorcross Grand Prix (MXGP) op het TT circuit van Assen op de agenda. Dit jaar kan een bijzondere editie worden, omdat Jeffrey Herlings de mogelijkheid heeft om de eerste Nederlandse wereldkampioen in de MXGP-categorie te worden.

Netherlands - Ministerie van Volksgezondheid, Welzijn en Sport

13-9-2018

BioLyte Laboratories Issues Voluntary Nationwide Recall Due to the Voluntary Nationwide Recall initiated by King Bio Inc. (a Raw Material Supplier) for NeoRelief for Muscle Cramping and Restlessness Topical Gel Due to Possible Microbial Contamination

BioLyte Laboratories Issues Voluntary Nationwide Recall Due to the Voluntary Nationwide Recall initiated by King Bio Inc. (a Raw Material Supplier) for NeoRelief for Muscle Cramping and Restlessness Topical Gel Due to Possible Microbial Contamination

BioLyte Laboratories is voluntarily recalling lot numbers 1138, 1139, 1146, and 1160 of NeoRelief for Muscle Cramping and Restlessness Topical Gel to the retail and consumer level. King Bio Inc., a manufacturer of some of the active ingredients in this product, has been found to have some water contamination issues that potentially could have affected this product. King Bio has issued a recall of these active ingredients in BioLyte’s lot specific product. To date, there have been no reports of illness or...

FDA - U.S. Food and Drug Administration

13-9-2018

Optipet ad us. vet., Ungezieferhalsband fuer Hunde

Optipet ad us. vet., Ungezieferhalsband fuer Hunde

● Die Neuzulassung erfolgte am 13.09.2018.

Institut für Veterinärpharmakologie und toxikologie

13-9-2018

Optipet ad us. vet., Ungezieferhalsband fuer Katzen

Optipet ad us. vet., Ungezieferhalsband fuer Katzen

● Die Neuzulassung erfolgte am 13.09.2018.

Institut für Veterinärpharmakologie und toxikologie

11-9-2018

Update of the Xylella spp. host plant database

Update of the Xylella spp. host plant database

Published on: Mon, 10 Sep 2018 00:00:00 +0200 Following a request from the European Commission, EFSA periodically updates the database on the host plants of Xylella spp. While previous editions of the database (2015 and 2016) dealt with the species Xylella fastidiosa only, this database version addresses the whole genus Xylella, including therefore both species X. fastidiosa and Xylella taiwanensis. The database now includes information on host plants of Xylella spp. retrieved from scientific literature...

Europe - EFSA - European Food Safety Authority Publications

11-9-2018

Modelling of inactivation through heating for quantitative microbiological risk assessment (QMRA)

Modelling of inactivation through heating for quantitative microbiological risk assessment (QMRA)

Published on: Mon, 27 Aug 2018 00:00:00 +0200 EFSA regards the household as a stage in the food chain that is important for the final number of food‐borne infections. The fate of a pathogen in the private kitchen largely depends on consumer hygiene during preparation of food and on its proper cooking, especially in the case of meat. Unfortunately, detailed information on the microbiological survival in meat products after heating in the consumer kitchen is lacking. The aim of the study was to improve th...

Europe - EFSA - European Food Safety Authority Publications

11-9-2018

Identification and evaluation of potentially mutagenic and carcinogenic food contaminants

Identification and evaluation of potentially mutagenic and carcinogenic food contaminants

Published on: Mon, 27 Aug 2018 00:00:00 +0200 Heat processing of food gives rise to a plethora of chemical compounds whose toxicological effects are largely unknown. Due to a general lack of experimental toxicological data, assessing the risks associated with the consumption of these substances remains a challenge. Computer models that allow for an in silico prediction of physicochemical and toxicological characteristics, may be able to fill current data gaps and facilitate the risk assessment of toxico...

Europe - EFSA - European Food Safety Authority Publications

10-9-2018

September 6, 2018: Cattle Company and Veterinarian Indicted for False Health Certificates on Livestock

September 6, 2018: Cattle Company and Veterinarian Indicted for False Health Certificates on Livestock

September 6, 2018: Cattle Company and Veterinarian Indicted for False Health Certificates on Livestock

FDA - U.S. Food and Drug Administration

7-9-2018

PET Ungezieferhalsband fuer Hunde ad us. vet.

PET Ungezieferhalsband fuer Hunde ad us. vet.

● Änderung Text: "Zusammensetzung", "Indikationen" und "Packungen"

Institut für Veterinärpharmakologie und toxikologie

7-9-2018

PET Ungezieferhalsband fuer Katzen ad us. vet.

PET Ungezieferhalsband fuer Katzen ad us. vet.

● Änderung Text "Zusammensetzung", "Indikationen" und "Packungen"

Institut für Veterinärpharmakologie und toxikologie

4-9-2018

Bovilis Blue-8 ad us. vet., Injektionssuspension fuer Rinder und Schafe

Bovilis Blue-8 ad us. vet., Injektionssuspension fuer Rinder und Schafe

● Die Neuzulassung erfolgte am 04.09.2018.

Institut für Veterinärpharmakologie und toxikologie

31-8-2018

Alcon Announces Voluntary Global Market Withdrawal of CyPass Micro-Stent for Surgical Glaucoma

Alcon Announces Voluntary Global Market Withdrawal of CyPass Micro-Stent for Surgical Glaucoma

Reflecting its uncompromising commitment to patient safety, Alcon today announced an immediate, voluntary market withdrawal of the CyPass Micro-Stent from the global market. In addition, Alcon advises surgeons to immediately cease further implantation with the CyPass Micro-Stent and to return any unused devices to Alcon. This decision and corresponding recommendation is based on an analysis of five-year post-surgery data from the COMPASS-XT long-term safety study. The US Food and Drug Administration (FD...

FDA - U.S. Food and Drug Administration

31-8-2018

Danish Medicines Agency launches new concept for National Scientific Advice

Danish Medicines Agency launches new concept for National Scientific Advice

Today, 31 August 2018, the Danish Medicines Agency is launching a new concept for National Scientific Advice for companies, hospitals and others who request advice on the requirements applicable to clinical investigation and marketing authorisations.

Danish Medicines Agency

30-8-2018

Grant agreement for piloting the Framework Partnership Agreement between the National data provider organisations in Denmark and EFSA – Final report

Grant agreement for piloting the Framework Partnership Agreement between the National data provider organisations in Denmark and EFSA – Final report

Published on: Tue, 07 Aug 2018 00:00:00 +0200 During the project seven standard operating procedures (SOP) were developed for the four data domains (zoonoses, chemical contaminant, pesticide residues and veterinary medical products residues). The SOPs describe 1) How the national governance of risk assessment data is organised, 2) how data are collected and validated before delivering to EFSA covering all four domains, 3) How data is transferred to EFSA, 4) how to respond to EFSA request for clarificati...

Europe - EFSA - European Food Safety Authority Publications

19-10-2018

New Safety Communication. @US_FDA   is sharing Updated Information To Reduce Potential Cardiac Surgery   Infection Risks Associated With the LivaNova 3T Heater-Cooler Systems. Read More:  https://go.usa.gov/xPnNW  #FDA #MedicalDevice

New Safety Communication. @US_FDA is sharing Updated Information To Reduce Potential Cardiac Surgery Infection Risks Associated With the LivaNova 3T Heater-Cooler Systems. Read More: https://go.usa.gov/xPnNW  #FDA #MedicalDevice

New Safety Communication. @US_FDA is sharing Updated Information To Reduce Potential Cardiac Surgery Infection Risks Associated With the LivaNova 3T Heater-Cooler Systems. Read More: https://go.usa.gov/xPnNW  #FDA #MedicalDevice

FDA - U.S. Food and Drug Administration

17-10-2018

Save the date & Join the @US_FDA’s  Patient Engagement Advisory Committee on Nov 15th to discuss  patient-generated health data from sources like social media, activity  trackers, and patient-driven registries. Learn more:  https://go.usa.gov/xPRau  #Digi

Save the date & Join the @US_FDA’s Patient Engagement Advisory Committee on Nov 15th to discuss patient-generated health data from sources like social media, activity trackers, and patient-driven registries. Learn more: https://go.usa.gov/xPRau  #Digi

Save the date & Join the @US_FDA’s Patient Engagement Advisory Committee on Nov 15th to discuss patient-generated health data from sources like social media, activity trackers, and patient-driven registries. Learn more: https://go.usa.gov/xPRau  #DigitalHealth #PEAC2018 pic.twitter.com/NU61Snpxxw

FDA - U.S. Food and Drug Administration

15-10-2018

We have created a rumor control page for Hurricane #Michael that will be updated regularly. Help us share this info and remember to always check with official sources like @FLSERT, @GeorgiaEMA and @femaregion4.

 http://fema.gov/hurricane-michael-rumor-co

We have created a rumor control page for Hurricane #Michael that will be updated regularly. Help us share this info and remember to always check with official sources like @FLSERT, @GeorgiaEMA and @femaregion4. http://fema.gov/hurricane-michael-rumor-co

We have created a rumor control page for Hurricane #Michael that will be updated regularly. Help us share this info and remember to always check with official sources like @FLSERT, @GeorgiaEMA and @femaregion4. http://fema.gov/hurricane-michael-rumor-control … pic.twitter.com/T3h7ZiFUrZ

FDA - U.S. Food and Drug Administration

10-10-2018

Diversity in research means more treatments work for more people. Join #ResearchDiversity Day on October 23rd for a day-long discussion of diversity in study recruitment and research. Join us! @Alzheimers_NIHpic.twitter.com/AwYhetCBiw

Diversity in research means more treatments work for more people. Join #ResearchDiversity Day on October 23rd for a day-long discussion of diversity in study recruitment and research. Join us! @Alzheimers_NIHpic.twitter.com/AwYhetCBiw

Diversity in research means more treatments work for more people. Join #ResearchDiversity Day on October 23rd for a day-long discussion of diversity in study recruitment and research. Join us! @Alzheimers_NIH pic.twitter.com/AwYhetCBiw

FDA - U.S. Food and Drug Administration

4-10-2018

Progestogel

Rote - Liste

1-10-2018

Diclofenac-ratiopharm 30 mg/g Gel

Rote - Liste

28-9-2018

Diclofenac AbZ 30 mg/g Gel

Rote - Liste

19-9-2018

Diclofenac acis 30 mg/g Gel

Rote - Liste

14-9-2018

Federal Register Notice: #FDA Request for Nominations of Voting Members on a Public Advisory Committee; National Mammography Quality Assurance Advisory Committee. Nominations are due by November 5, 2018. For more information, click here:  https://go.usa.g

Federal Register Notice: #FDA Request for Nominations of Voting Members on a Public Advisory Committee; National Mammography Quality Assurance Advisory Committee. Nominations are due by November 5, 2018. For more information, click here: https://go.usa.g

Federal Register Notice: #FDA Request for Nominations of Voting Members on a Public Advisory Committee; National Mammography Quality Assurance Advisory Committee. Nominations are due by November 5, 2018. For more information, click here: https://go.usa.gov/xPgW5  #MedicalDevice

FDA - U.S. Food and Drug Administration

14-9-2018

Federal Register Notice: Request for Nominations on Public Advisory Panels of the Medical Devices Advisory Committee. Nominations are due by October 9, 2018. For more information, click here:  https://go.usa.gov/xPgWa  #MedicalDevice

Federal Register Notice: Request for Nominations on Public Advisory Panels of the Medical Devices Advisory Committee. Nominations are due by October 9, 2018. For more information, click here: https://go.usa.gov/xPgWa  #MedicalDevice

Federal Register Notice: Request for Nominations on Public Advisory Panels of the Medical Devices Advisory Committee. Nominations are due by October 9, 2018. For more information, click here: https://go.usa.gov/xPgWa  #MedicalDevice

FDA - U.S. Food and Drug Administration

14-9-2018

Federal Register Notice: #FDA Request for Nominations for Voting Members on a Public Advisory Committee; Technical Electronic Product Radiation Safety Standards Committee. Nominations are due by November 5, 2018. For more information, click here: https://

Federal Register Notice: #FDA Request for Nominations for Voting Members on a Public Advisory Committee; Technical Electronic Product Radiation Safety Standards Committee. Nominations are due by November 5, 2018. For more information, click here: https://

Federal Register Notice: #FDA Request for Nominations for Voting Members on a Public Advisory Committee; Technical Electronic Product Radiation Safety Standards Committee. Nominations are due by November 5, 2018. For more information, click here: https://go.usa.gov/xPgDd 

FDA - U.S. Food and Drug Administration

3-9-2018

Virudermin, Gel

Rote - Liste