البلد: الولايات المتحدة
اللغة: الإنجليزية
المصدر: NLM (National Library of Medicine)
LITHIUM CARBONATE (UNII: 2BMD2GNA4V) (LITHIUM CATION - UNII:8H8Z5UER66)
Golden State Medical Supply, Inc.
LITHIUM CARBONATE
LITHIUM CARBONATE 150 mg
PRESCRIPTION DRUG
Abbreviated New Drug Application
LITHIUM CARBONATE- LITHIUM CARBONATE CAPSULE GOLDEN STATE MEDICAL SUPPLY, INC. ---------- LITHIUM CARBONATE CAPSULES, USP REV. 05/15 RX ONLY WARNING Lithium toxicity is closely related to serum lithium levels, and can occur at doses close to therapeutic levels. Facilities for prompt and accurate serum lithium determinations should be available before initiating therapy. (see DOSAGE AND ADMINISTRATION). DESCRIPTION Each capsule for oral administration contains 150 mg, 300 mg or 600 mg of lithium carbonate. In addition, each capsule contains the following inactive ingredient: 150 mg: Talc. 300 mg: Talc. Capsule shell for the 150 mg potency contains: Gelatin and Titanium Dioxide. Capsule shell for the 300 mg potency contains: D&C Yellow #10, FD&C Green #3, FD&C Red #40, FD&C Yellow #6, Gelatin and Titanium Dioxide. Capsule shell for the 600 mg potency contains: Titanium Dioxide, Gelatin and FD&C Red #40. The printing ink contains: D&C Yellow #10, FD&C Blue #1, FD&C Blue #2, FD&C Red #40, n-Butyl Alcohol, Pharmaceutical Glaze, Propylene Glycol, SDA-3A Alcohol, and Synthetic Black Iron Oxide. Lithium is an element of the alkali-metal group with atomic number 3, atomic weight 6.94, and an emission line at 671 nm on the flame photometer. Lithium Carbonate is a white, light, alkaline powder with molecular formula Li CO and molecular weight 73.89. CLINICAL PHARMACOLOGY Preclinical studies have shown that lithium alters sodium transport in nerve and muscle cells and effects a shift toward intraneuronal metabolism of catecholamines, but the specific biochemical mechanism of lithium action in mania is unknown. INDICATIONS AND USAGE Lithium is indicated in the treatment of manic episodes of Bipolar Disorder. Bipolar Disorder, Manic (DSM-III) is equivalent to Manic Depressive illness, Manic, in the older DSM-II terminology. Lithium is also indicated as a maintenance treatment for individuals with a diagnosis of Bipolar Disorder. Maintenance therapy reduces the frequency of manic episodes and diminishes the intensity of those e اقرأ الوثيقة كاملة