البلد: كندا
اللغة: الإنجليزية
المصدر: Health Canada
CHLORPROMAZINE (CHLORPROMAZINE HYDROCHLORIDE)
SANOFI-AVENTIS CANADA INC
N05AA01
CHLORPROMAZINE
25MG
LIQUID
CHLORPROMAZINE (CHLORPROMAZINE HYDROCHLORIDE) 25MG
ORAL
500ML
Prescription
PHENOTHIAZINES
Active ingredient group (AIG) number: 0106167001; AHFS:
CANCELLED POST MARKET
2006-07-28
PRESCRIBING INFORMATION LARGACTIL CHLORPROMAZINE HYDROCHLORIDE DROPS 40 MG/ML CHLORPROMAZINE HYDROCHLORIDE SUPPOSITORIES 100 MG CHLORPROMAZINE HYDROCHLORIDE LIQUID 25 MG/ML _ _ NEUROLEPTIC sanofi-aventis Canada Inc. Revision Date: 2150 St. Elzear Blvd. West October 13, 2006 Laval, Quebec H7L 4A8 Submission Control No. 107341 s-a version 3.0 dated _Page 2 of 11_ NAME OF DRUG LARGACTIL CHLORPROMAZINE HYDROCHLORIDE DROPS CHLORPROMAZINE HYDROCHLORIDE SUPPOSITORIES CHLORPROMAZINE HYDROCHLORIDE LIQUID THERAPEUTIC CLASSIFICATION Neuroleptic ACTION Chlorpromazine is a phenothiazine of the aminopropyl group. It is a potent antipsychotic and sedative agent which can control various states of emotional tension, agitation, hyperactivity and confusion. In addition, it exerts an anti-emetic action and potentiates the effects of narcotics, barbiturates and analgesics. INDICATIONS In psychiatry - schizophrenia, manic depressive psychoses (manic phase), behavioural disorders, involutional psychoses, senile psychoses and confusional states in the elderly. In general medicine - nausea, vomiting; persistent hiccup and organic conditions associated with emotional stress: acute or chronic alcoholism and for the treatment of withdrawal symptoms of addicts and alcoholics. In obstetrics and surgery - as a preoperative medication for the relief of apprehension; to reduce, by potentiation, narcotic and analgesic requirements; as an antiemetic; to prevent and treat traumatic or postoperative shock; for use in artificial hibernation and controlled hypotension. _Page 3 of 11_ CONTRAINDICATIONS Severe CNS depression or comatose states due to alcohol, barbiturates, analgesics or other CNS depressants. In patients with blood dyscrasias, severe liver disease or a sensitivity to phenothiazines. WARNINGS As with other neuroleptics, very rare cases of QT interval prolongation have been reported with LARGACTIL. Neuroleptic phenothiazines may potentiate QT interval prolongation, which increases the risk of onset of serious ventricular arrhythmias of t اقرأ الوثيقة كاملة